Infant Care, Daycare, and Preschool in Mission Valley

A centrally located early learning center for children from 6 weeks through Pre-K. Families from across central San Diego come to us for small classrooms, teachers who truly know their children, and a campus kids are excited to walk into every morning.

White, cloud-shaped silhouettes form a wavy border against a light gray background, creating a serene, stylized sky—perfect for infant care or preschool settings in San Diego.
Four young children play with colorful educational toys at a round table in a Mission Valley classroom, with bookshelves in the background and an adult partially visible, supervising this engaging preschool activity.

Programs at Our Mission Valley Center

Every age group has its own classroom, teachers, and daily rhythm, and children move up as they grow.

  • Infant Care (6 weeks to 12 months): Consistent caregivers, feeding and naps on your baby’s schedule, and daily updates on every bottle, nap, and milestone.
  • Toddler Program (1 to 2 years): Hands-on sensory play, early language, and lots of practice with independence.
  • Preschool (3 to 4 years): Early literacy, math, and social skills built through play and a predictable routine.
  • Pre-K (4 to 5 years): Kindergarten readiness, with early reading, writing, and the confidence to start school strong.

We enroll year-round, Monday through Friday, 7:30am to 5:30pm.

What Mission Valley Families Love About Us

Stay connected to their day. Parents tell us how much they appreciate the daily photos, videos, and updates from their child’s classroom.

A bright, open campus. Clean, airy classrooms and an outdoor play area that gets used every day.

Teachers who know your child. Small classrooms mean teachers learn each child’s personality, needs, and favorite things.

A real community. From our first-anniversary celebration to seasonal events, we bring families together throughout the year.

A secure building with easy drop-off and pickup. Getting in and out is simple, which makes busy mornings smoother.

A group of young children stand in a classroom, raising their arms and playing together during a lively preschool tour. Colorful decorations and drawings adorn the walls in the background, making it easy to see why this San Diego classroom is sure to be a highlight on any parent’s checklist.

A Convenient Central San Diego Location

We’re on Camino Del Rio South, just off I-8 near Mission Center Road. That’s an easy stop for families commuting downtown, to Kearny Mesa, or anywhere in central San Diego.

Families come to us from Mission Valley and nearby neighborhoods, including Hillcrest, Mission Hills, University Heights, Normal Heights, North Park, Old Town, Linda Vista, Serra Mesa, Kearny Mesa, and Clairemont.

Address

967 Camino Del Rio S
San Diego, CA 92108

Contact

Phone: 619-295-5500
Fax: 619-329-4555
License # 376105206

Hours

Monday-Friday 7:30am-5:30pm

Parent Reviews

What Mission Valley Parents Are Saying

Read more reviews from Mission Valley families on Google and Yelp.

Mission Valley FAQs

Is Nese Kids Care a daycare or a preschool?

Both. We’re an early learning center with infant care, toddler care, preschool, and Pre-K under one roof, so your child can stay with us from 6 weeks old until they start kindergarten.

Do you offer infant care in Mission Valley?

Yes. Our infant program welcomes babies starting at 6 weeks old, with consistent caregivers and feeding and nap routines that follow your baby’s schedule.

What ages do you serve in Mission Valley?

We care for children from 6 weeks old through Pre-K, with separate classrooms for infants, toddlers, preschoolers, and Pre-K.

Where are you located?

We’re at 967 Camino Del Rio South in San Diego, just off I-8 near Mission Center Road. It’s an easy drive from Hillcrest, Old Town, Kearny Mesa, and downtown.

What are your hours?

We’re open Monday through Friday, 7:30am to 5:30pm.

Is Nese Kids Care licensed?

Yes. Nese Kids Care Mission Valley is a licensed child care center in the State of California, facility number 376105206.

Can my child start mid-year?

Yes. We enroll year-round, so your child can start when you’re ready and a spot is available.

What age do kids start preschool?

Most children start preschool between ages 3 and 4, and our Preschool program begins at age 3. Readiness matters more than a birthday, so we’re happy to talk through where your child is today. Learn more in our guide, What Age Do Kids Start Preschool?

What should I ask when touring a preschool?

Ask about teacher experience, daily routines, communication with parents, and safety. Our preschool tour checklist covers the questions San Diego parents ask most.

How do I schedule a tour?

Use the scheduler on this page or call us at (619) 295-5500. We’d love to show you around, introduce you to our teachers, and answer your questions.

Do you have another location?

Yes. Our Ramona center at 2291 Main Street offers the same programs, with early drop-off starting at 6:30am.

A woman helps a boy with a learning activity using colorful blocks at a Toddler Care center in Mission Valley, while smaller images show children doing schoolwork and crafts with adult guidance.

Connect with Our Mission Valley Campus

See classroom moments, activities, and updates from our Mission Valley families.

Explore Our Locations

Nese Kids Care serves families across San Diego County. Find the location that works best for your family.

Not sure which location is best?
Contact us and our team can help you find the best fit.

Mission Valley

Childcare & Preschool in Central San Diego

Ramona

Infant Care, Childcare & Preschool in Ramona

Join the Nese Kids Care Family Today!

Give your child the gift of an exceptional early education experience that will lay the foundation for a lifetime of learning and growth. We invite you to become part of our community of families dedicated to nurturing children’s brightest futures.

Schedule a Tour

Visit our center to see our programs in action and meet our dedicated educators.

Enrollment Consultation

We'll discuss your child's needs and find the perfect program fit for your family.

Join Our Community

Complete enrollment and begin your child's journey with Nese Kids Care!

A young girl, enjoying early education play, stands on a bed blowing bubbles while a man and woman, both smiling, sit nearby and play with the bubbles in a bright, cozy room.
Minimalist drawing of a sloping ground with three thin lines and a single orange tree on the right, perfect for Early Education and Preschool settings, set against a light gray background for a calming effect.